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human crispr cas9 synergistic activation mediator sam sgrna library  (Addgene inc)


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    Structured Review

    Addgene inc human crispr cas9 synergistic activation mediator sam sgrna library
    Human Crispr Cas9 Synergistic Activation Mediator Sam Sgrna Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 27 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+crispr+cas9+synergistic+activation+mediator+sam+sgrna+library/Human+CRISPR+Activation+Library+(SAM+-+3+plasmid+system)+(Pooled+Library+%231000000057%2C+%231000000074)/pm39210147-232-2-14
    Average 93 stars, based on 27 article reviews
    human crispr cas9 synergistic activation mediator sam sgrna library - by Bioz Stars, 2026-10
    93/100 stars

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    Related Articles

    Genome Wide:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI = 0.5.

    Article Title: A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI=0.5.

    CRISPR:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI = 0.5.

    Article Title: A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI=0.5.

    Activation Assay:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI = 0.5.

    Article Title: A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI=0.5.

    Amplification:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI = 0.5.

    Article Title: A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI=0.5.

    Next-Generation Sequencing:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI = 0.5.

    Article Title: A noncanonical repressor function of JUN restrains YAP activity and suppresses YAP-dependent liver cancer growth
    Article Snippet: .. The genome-wide human CRISPR/Cas9 Synergistic Activation Mediator (SAM) sgRNA library (gift from Feng Zhang, Addgene #1000000057) was amplified as recommended, and balanced sgRNA library distribution was verified by NGS. .. Clonal MCF10A cells stably expressing SAM components (MCF10A-SAM cells), dCas9-VP64 and MCP-p65-HSF1 (gift from Feng Zhang, Addgene #61425 and #61426), were infected with the lentiviral SAM sgRNA library with a low titer of MOI=0.5.

    other:

    Article Title: A non-canonical repressor function of JUN restrains YAP activity and liver cancer growth.
    Article Snippet: Yes-associated protein (YAP) and its homolog, transcriptional coactivator with PDZ-binding motif (TAZ), are the main transcriptional downstream effectors of the Hippo pathway.. Decreased Hippo pathway activity leads to nuclear translocation of YAP/TAZ where they interact with TEAD transcription factors to induce target gene expression.. Unrestrained YAP/TAZ activity can lead to excessive growth and tumor formation in a short time, underscoring the evolutionary need for tight control of these two transcriptional coactivators.



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    93
    Addgene inc human crispr cas9 synergistic activation mediator sam sgrna library
    Human Crispr Cas9 Synergistic Activation Mediator Sam Sgrna Library, supplied by Addgene inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+crispr+cas9+synergistic+activation+mediator+sam+sgrna+library/Human+CRISPR+Activation+Library+(SAM+-+3+plasmid+system)+(Pooled+Library+%231000000057%2C+%231000000074)/pm39210147-232-2-14
    Average 93 stars, based on 1 article reviews
    human crispr cas9 synergistic activation mediator sam sgrna library - by Bioz Stars, 2026-10
    93/100 stars
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